Women's Health · 8 min read

Heart Disease in Women: Why Symptoms Look Different and Get Missed

Heart disease kills more women in the United States than all forms of cancer combined. Yet it remains dramatically underdiagnosed in women — often because symptoms present differently, risk factors are evaluated differently, and both patients and providers have historically underestimated cardiovascular risk in women. This is a problem with real consequences.

February 2025
ARDMS-Certified Sonographers

The Classic Heart Attack Myth

The image most people have of a heart attack — a man clutching his chest and left arm, sweating profusely — reflects how heart attacks commonly present in men. Women's heart attacks frequently look completely different, and this difference has contributed to decades of delayed diagnosis and worse outcomes.

Women are more likely to experience heart attack symptoms that include unusual fatigue (not exertion-related — just persistent, profound tiredness), jaw pain, neck pain, or upper back pain rather than classic chest pain, nausea or indigestion-like discomfort, shortness of breath without chest pain, and lightheadedness or dizziness.

These symptoms are easier to dismiss — as anxiety, stress, the flu, or gastrointestinal issues. Women are more likely to wait longer before seeking emergency care, and when they do arrive, research shows they are less likely to receive the same aggressive evaluation and treatment as men with equivalent symptoms.

Why Women's Hearts Age Differently

Women's cardiovascular risk increases dramatically after menopause. Estrogen has protective effects on blood vessels — it helps maintain flexible artery walls, supports healthy cholesterol levels, and reduces inflammation. When estrogen declines at menopause, cardiovascular risk rises sharply. A woman who had lower cardiovascular risk than a man of the same age at 45 may have equivalent or higher risk by 65.

Women are also more susceptible to certain cardiac conditions that affect men less frequently. Spontaneous coronary artery dissection (SCAD) — a tear in the coronary artery wall — occurs primarily in younger women and often without the traditional risk factors. Takotsubo syndrome (stress cardiomyopathy, sometimes called "broken heart syndrome") is triggered by acute emotional or physical stress and is far more common in postmenopausal women. Neither condition shows up on a standard EKG the way a typical heart attack does.

The Role of Preventive Screening

Because women's heart disease is so often silent until a major event, preventive imaging is particularly important. An echocardiogram evaluates cardiac structure and function — detecting cardiomyopathy, valvular disease, and reduced ejection fraction — regardless of whether symptoms are present.

A carotid ultrasound assesses atherosclerotic burden in the neck arteries and provides a window into overall vascular health. High blood pressure, often undertreated in women, accelerates carotid plaque formation and is one of the strongest modifiable risk factors for stroke.

Traditional cardiovascular my health scores have historically underestimated risk in women. Factors that are more cardiovascular-significant in women include autoimmune conditions (lupus, rheumatoid arthritis), a history of preeclampsia or gestational hypertension, polycystic ovarian syndrome (PCOS), and premature menopause before age 40. If any of these apply to you, your cardiovascular risk may be higher than a standard calculator suggests.

Taking Action

The most important thing any woman can do is not wait for symptoms to seek evaluation. Cardiovascular screening is appropriate for women over 50, women with any of the risk factors above, and women with a family history of early heart disease — regardless of how healthy they feel.

At BlackPoint Diagnostics, we offer echocardiograms and vascular screenings at your home or workplace, no referral required. We believe every woman deserves access to the same quality cardiovascular imaging that's available in major medical centers — without the barriers of long waits, referrals, and inconvenient appointments.

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